Publications

2019

INT. JOURNAL OF CANCER            Volume: 0                             Published: January 2019                                DOI: 10.1002/ijc.32137.
Susan Bengs, Eugenia Becker, Philipp Busenhart, Marianne R. Spalinger, Tina Raselli, Stephanie Kasper, Silvia Lang, Kirstin Atrott, Celine Mamie, Stephan R. Vavricka, Lotta von Boehmer, Alexander Knuth, Anne Tuomisto, Markus J. Mäkinen, Petr Hruz, Matthias Turina, Andreas Rickenbacher, Henrik Petrowsky, Achim Weber, Pascal Frei, Marcel Halama, Gisli Jenkins, Dean Sheppard, Roland S. Croner, Jan Christoph, Nathalie Britzen-Laurent, Elisabeth Naschberger, Vera Schellerer, Michael Stürzl, Michael Fried, Gerhard Rogler, Michael Scharl

β6-integrin serves as a novel serum tumor marker for colorectal carcinoma
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NATURE                                       Volume: 566                          Published: January 2019                            DOI:10.1038/s41586-019-0899-7.
Konrad Gronke, Pedro P. Hernández, Jakob Zimmermann, Christoph S. N. Klose, Michael Koefoed-Branzk, Fabian Guendel, Mario Witkowski, Caroline Tizian, Lukas Amann, Fabian Schumacher, Hansruedi Glatt, Antigoni Triantafyllopoulou, Andreas Diefenbach

Interleukin-22 protects intestinal stem cells against genotoxic stress
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NATURE IMMONOLOGY                   Volume: 0                           Published: February 2019                            DOI: 10.1038/s41590-019-0316-2.
Christian Neumann, Jonas Blume, Urmi Roy, Peggy P. Teh, Ajithkumar Vasanthakumar, Alexander Beller, Yang Liao, Frederik Heinrich, Teresita L. Arenzana, Jason A. Hackney, Celine Eidenschenk, Eric J. C. Gálvez, Christina Stehle, Gitta A. Heinz, Patrick Maschmeyer, Tom Sidwell, Yifang Hu, Derk Amsen, Chiara Romagnani, Hyun-Dong Chang, Andrey Kruglov, Mir-Farzin Mashreghi, Wei Shi, Till Strowing, Sascha Rutz, Axel Kallies, Alexander Scheffold

c-Maf-dependent T-reg-cell control of intestinal T-H-17 cells and IgA establishes host-microbiota homeostasis
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CELL                                            Volume: 0                           Published: February 2019                               DOI:10.1016/j.cell.2019.01.041.
Petra Bacher, Thordis Hohnstein, Eva Beerbaum, Marie Röcker, Matthew G. Blango, Svenja Kaufmann, Jobst Röhmel, Patience Eschenhagen, Claudia Grehn, Kathrin Seidel, Volker Rickerts, Laura Lozza, Ulrik Stervbo, Mikalai Nienen, Nina Babel, Julia Milleck, Mario Assenmacher, Oliver A. Cornely, Maren Ziegler, Hilmar Wisplinghoff, Guido Heine, Margitta Worm, Britta Siegmund, Jochen Maul, Petra Creutz, Christoph Tabeling, Chistoph Ruwwe-Glösenkamp, Leif E. Sander, Christoph Knosalla, Sascha Brunke, Bernhard Hube, Olaf Kniemeyer, Axel A. Brakhage, Carsten Schwarz, Alexander Scheffold

Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans
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2018

FRONTIERS IN IMMUNOLOGY                Volume: 9               Published: May 2018               DOI: 10.3389/fimmu.2018.01171
Moritz Leppkes, Britta Siegmund and Christoph Becker

Editorial: Immune-Epithelial Crosstalk in Inflammatory Bowel Diseases and Mucosal Wound Healing.
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FRONTIERS IN IMMUNOLOGY             Volume: 9                Published: July 2018                   DOI: 10.3389/fimmu.2018.01700
Timo Rath, Ulrike Billmeier, Fulvia Ferrazzi, Michael Vieth, Arif Ekici, Markus F. Neurath, Raja Atreya

Effects of Anti-Integrin Treatment With Vedolizumab on Immune Pathways and Cytokines in Inflammatory Bowel Diseases
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NATURE IMMUNOLOGY                     Volume: 19               Published: August 2018               DOI: 10.1038/s41590-018-0163-6
Quirin Hammer, Timo Rückert & Chiara Romagnani

Natural killer cell specificity for viral infections
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BIOCHEMICAL JOURNAL                  Volume: 475               Published: August 2018               DOI: 10.1042/BCJ20180123
Bea Unterer, Veit Wiesmann, Mekala Gunasekaran, Heinrich Sticht, Clara Tenkerian, Jürgen Behrens, Marina Leone, Felix B. Engel, Nathalie Britzen-Laurent, Elisabeth Naschberger, Thomas Wittenberg, Michael Stürzl

IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD
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MUCOSAL IMMUNOLOGY                Volume: 11                 Published: August 2018               DOI: 10.1038/s41385-018-0068-6
Barbara Ruder, Vinay Murtadak, Michael Stürzl, Stefan Wirtz, Ute Distler, Stefan Tenzer, Mousumi Mahapatro, Florian R. Greten, Yinling Hu, Markus F. Neurath, Ethel Cesarman, Gianna Ballon, Claudia Günther, Christoph Becker

Chronic intestinal inflammation in mice expressing viral Flip in epithelial cells
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FRONT IMMUNOLOGY                     Volume: 9                  Published: October 2018               DOI:10.3389/fimmu.2018.01974
Carl Weidinger, Jörn F. Ziegler, Marilena Letizia, Franziska Schmidt, Britta Siegmund

Adipokines and Their Role in Intestinal Inflammation
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LANCET GASTRO. and HEPAT.        Volume: 3                  Published: November 2018           DOI:10.1016/S2468-1253(18)30265-6
Raja Atreya, Markus F. Neurath 

Mechanisms of molecular resistance and predictors of response to biological therapy in inflammatory bowel disease
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NUTRIENTS                                    Volume:10                 Published: November 2018             DOI: 10.3390/nu10111796.
Alice Itzlinger, Federica Branchi, Luca Elli, Michael Schumann 

Gluten-Free Diet in Celiac Disease – Forever and for All?
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IMMUNOLOGICAL REVIEWS         Volume: 286               Published: November 2018              DOI:10.1111/imr.12712.
Christina Stehle, Daniela C. Hernández, Chiara Romagnani

Innate lymphoid cells in lung infection and immunity
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GASTROENTEROLOGY                Volume: 0                   Published: November 2018              DOI:10.1053/j.gastro.2018.11.029.
Kristina Scheibe, Christina Kersten, Anabel Schmied, Michael Vieth, Tatjana Primbs, Birgitta Carlé, Ferdinand Knieling, Jing Claussen, Alexander C. Klimowicz, Jie Zheng, Patrick Baum, Sebastian Meyer, Sebastian Schürmann, Oliver Friedrich, Maximilian J. Waldner, Timo Rath, Stefan Wirtz, George Kollias, Arif B. Ekici, Raja Atreya, Ernest L. Raymond, M. Lamine Mbow, Markus F. Neurath, Clemens Neufert

Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation
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INT J OF COLORECTAL DISEASE    Volume: 34             Published: November 2018              DOI: 10.1007/s00384-018-3198-0.
Vera S. Schellerer, Melanie C. Langheinrich, Veronika Zver, Robert Grützmann, Michael Stürzl, Olaf Gefeller, Elisabeth Naschberger, Susanne Merkel 

Soluble intercellular adhesion molecule-1 is a prognostic marker in colorectal carcinoma
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AMERICAN JOURNAL GASTROENTEROLOGY            Volume: 113             Published: December 2018              DOI: 10.1038/s41395-018-0394-z.
Sebastian Zundler, Lisa Dietz, Klaus Matzel, Carol-Immanuel Geppert, Emily Becker, Timo Rath, Markus F. Neurath, Raja Atreya 

Successful Long-term Treatment of Diversion Colitis with Topical Coconut Oil Application
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J OF ALLERGY & CLINICAL IMMUNOLOGY                 Volume: 142             Published: December 2018             DOI: 10.1016/j.jaci.2018.10.016.
Petra Bacher, Alexander Scheffold 

The effect of regulatory T cells on tolerance to airborne allergens and allergen immunotherapy
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THERANOSTICS                                  Volume: 8                            Published: December 2018                          DOI: 10.7150/thno.26013
Dennis Jung, Rafael Heiss, Viktoria Kramer, Oana-Maria Thoma, Adrian P. Regensburger, Wolfgang Rascher, Michael Uder, Markus F. Neurath, Ferdinand Knieling, Maximilian J. Waldner 

Contrast-Enhanced μCT for Visualizing and Evaluating Murine Intestinal Inflammation
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NATURE NEUROSCIENCE                   Volume: 22                        Published: December 2018                        DOI: 10.1038/s41593-018-0290-2.
Chotima Böttcher, Stephan Schlickeiser, Marjolein A. M. Sneeboer, Desiree Kunkel, Anniki Knop, Evdokia Paza, Pawel Fidzinski, Larissa Kraus, Gijsje J. L. Snijders, René S. Kahn, Axel R. Schulz, Henrik E. Mei, NBB-Psy, Elly M. Hol, Britta Siegmund, Rainer Glauben, Eike J. Spruth, Lot D. de Witte, Josef Priller 

Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry
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